Background to IBIS-II Prevention
The IBIS-II study has grown from the IBIS-I Study. The International Breast Cancer Intervention Study I (IBIS-I) was designed to investigate the use of tamoxifen in preventing breast cancer in women with a higher risk of developing the disease.
Recruitment of women to IBIS-I ended in March 2001 and the results of the study showed that tamoxifen reduced the incidence of breast cancer by one third in these high risk women but with some serious side effects.
IBIS-II was designed to continue the work started in IBIS-I by examining the role of anastrozole in the prevention of breast cancer.
